Glutathione Synthesis Explained: How Your Body Builds Its Master Antioxidant OrganiClinic Frontiers Regulation of epigenetic traits of the glutathione S transferase P1 gene: from detoxification toward cancer prevention and diagnosis Methyl Group Metabolism in Differentiation, Aging, and Cancer PRMT1 mediated methylation of UBE2m promoting calcium oxalate crystal induced kidney injury by inhibiting fatty acid metabolism Cell Death & Disease Estrogen Metabolism, Detoxification, and Methylation Dr. Daniel Metzger, DACM, L.Ac. When people think about detox, they usually think about the liver. But detoxification actually involves several systems working together. One of the most important is methylation. Methylation supports processes involved in