Pentose Phosphate Pathway made simple. This pathway has two major jobs: Generate NADPH Produce ribose 5 phosphate NADPH protects cells from oxidative stress and supports fatty acid, cholesterol, steroid, nitric oxide, and respiratory burst Divergent effects of glutathione depletion on isocitrate dehydrogenase 1 and the pentose phosphate pathway in hamster liver Jin 2020 Physiological Reports Wiley Online Library The Pivotal Role of One Carbon Metabolism in Neoplastic Progression During the Aging Process Glutathione Related Enzymes and Proteins: A Review HMP Pathway Simplified: NADPH Role & G6PD Deficiency Explained Glutathione an overview ScienceDirect Topics