A 48 hour fast can turn standard Paracetamol into acute liver failure. Fasting depletes Glutathione, leaving the liver defenseless against toxic NAPQI. Review the latest guidelines on BMJ Best Practice: https: bestpractice.bmj.com topics en us 1010 Chronic Glutathione Depletion Confers Protection against Alcohol induced Steatosis: Implication for Redox Activation of AMP activated Protein Kinase Pathway Scientific Reports 9 Health Benefits of Glutathione Day 2 of 15: Glutathione + Your Liver We talk a lot about liver health, detox diets, cutting alcohol, avoiding processed food. All valuable. But the foundational piece most people skip? The What are the adverse effects of intravenous glutathione in patients with liver disease? Glutathione IV Therapy: What You Need to Know COEM