B 12 (Cyanocobalamin) Shot Therapy MedClub by Dr Jenn Hi Dr. Tony here! If you give yourself injectionstestosterone, estrogen, insulin, peptides, or B12these are 3 of my favorite tips to make them almost painless. Tip 1: Insert the needle quickly, then Treating Severe Vitamin B12 Deficiency B12 IM Injection How to Self Administer Subcutaneous & Intramuscular Injections Self Administering B12 Injections: A Step by Step Guide How To Give Yourself Vitamin B12 Shots (with video!)