The Role of Microbiome in Cardiovascular Health: Insights for Primary Care Interventions Cureus Gut Microbiome Derived Metabolite Trimethylamine N Oxide Induces Aortic Stiffening and Increases Systolic Blood Pressure With Aging in Mice and Humans Hypertension TMAO biosynthesis. L carnitine and choline are derived from the diet Download Scientific Diagram Identification of TMAO producer phenotype and hostdietgut dysbiosis by carnitine challenge test in human and germ free mice Gut Simultaneous quantification of trimethylamine oxide and its precursors from gut microbial metabolic pathway Comparison of short term and long term effects of peroral L carnitine intake: clinical implications of elevated TMAO levels in cardiovascular complications