Places for Intramuscular Injection: 4 Safe Spots Not all shots are the same here's a guide Injections are a fast, effective way to deliver medications, nutrients, and vaccines directly into the body but not all injections are the same. Best Vitamin B12 Injection Site: Administering B12 Shots Treating Severe Vitamin B12 Deficiency B12 IM Injection Subcutaneous (SC) and Intramuscular (IM) Injections Must Knows for Subcutaneous administration: Pinch skin with non dominant hand and hold syringe with dominant hand Always inject: 2 inches away from umbilicus (for abdomen) 3 inches B12 Shots at Home: How, Where & How Often to Inject Yourself AZ IV Medics