A Possible Antidote for Tylenol (Paracetamol) Overdose American Council on Science and Health Acetaminophen's Role in Autism and ADHD: A Mitochondrial Perspective Glutathione, Alcohol and drugs GSH reduces NAPQI, the metabolite responsible for hepatotoxicity in acetaminophen toxicity. Toxic doses increase oxidation into NAPQI, overwhelming glutathione. How does ethanol interfere with acetaminophen metabolism? Image: https: t.co 6EY9dIwLXY Paracetamol (Acetaminophen) and the Developing Brain Tylenol and glutathione, actually explainedhere's the bullet points: * Lots of concern raised on social media re: glutathione depletion and acetaminophen use * Glutathione is used in the metabolism of acetaminophen and