Regulation of thyroid hormone production DIO = deiodinase; GPx = Download Scientific Diagram Lesson: Thyroid Disease: A Delicate Balance Disrupted Selenium and Prebiotics as Adjunctive Therapies in Treatment of Graves' Disease IntechOpen Supplementation with antioxidants in the treatment of Graves' disease; the effect on glutathione peroxidase activity and concentration of selenium ScienceDirect How to Increase Glutathione to Protect Against Hashimoto's Graves' disease impacts the body by causing the immune system to attack the thyroid gland, leading to an overproduction of thyroid hormones. This excess can trigger a wide range of symptoms, including