Glutathione contributes to efficient post Golgi trafficking of incoming HPV16 genome PLOS One Combined inhibition of de novo glutathione and nucleotide biosynthesis is synthetically lethal in glioblastoma ScienceDirect The glutathione cycle shapes synaptic glutamate activity bioRxiv Glutathione concentration in BSO treated, BSO and NAC co treated, NAC Download Scientific Diagram 5 6) By contrast, latency I Burkitt B cells were particularly vulnerable to ferroptosis induction by blockade of either cystine import, glutathione synthesis or glutathione peroxidase 4 (GPX4). Eric also found roles for Exploring the Lean Phenotype of Glutathione Depleted Mice: Thiol, Amino Acid and Fatty Acid Profiles PLOS One
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bso glutathione The glutathione synthesis inhibitor buthionine sulfoximine synergistically enhanced melphalan activity against preclinical models of multiple myeloma