Sites of Administration of Subcutaneous injection Optimal B12 Injection Sites for Maximum Absorption and Benefits Your Health Magazine How B12 & Lipo Injections Support Weight Loss Efforts What Should You Know About Vitamin B12 Injections? Happy Hands Aesthetics Safe IM Injection Site Intramuscular injection should always be given in the **upper outer quadrant of the gluteal region** to prevent sciatic nerve injury. Key nursing points: Upper outer quadrant = Figure. Anatomical markers used to identify the vastus lateralis injection site on the anterolateral thigh The Australian Immunisation Handbook