Mucosal melanocytic macules What Caused These Multiple Hyperpigmented Macules of the Mouth? Melanotic Macule Lip Removal TikTok Dental Update Malignant oral melanoma: how to spot it and how it is managed Dental Update Labial Macules: Dark Spots on the Lip Dermatology Advisor This patient has multiple labial melanotic macules. These are essentially freckles of the lips. These most commonly involve the lower lip. This patient had involvement of both the upper and lower lips.